Preoperative anaemia and thrombocytosis predict adverse prognosis in non‐metastatic renal cell carcinoma with tumour thrombus

Abstract Background This study aimed to determine the prognostic value of preoperative blood parameters in renal cell carcinoma (RCC) and tumour thrombus (TT) patients that were surgically treated. Method We retrospectively analysed clinicopathological data 146 RCC TT Univariate or multivariate Cox regression analyses performed risk factors associated with progression-free survival (PFS) overall (OS). Kaplan-Meier analysis logistic factors. Receiver operating characteristic curves applied test improvements predictive accuracy established prognosis score. Results On univariate analysis, anaemia (HR 2.873, P = 0.008) lymph node metastasis 4.811, 0.015) independent linked OS. Besides, thrombocytosis 2.324, 0.011), histologic subtype 2.835, 0.004), nuclear grade 2.069, 0.033), 5.739, 0.001) PFS. Kaplan–Meier revealed exhibited worse OS than those without it (P 0.0033). Likewise, showed PFS < 0.0001). Adding SSIGN score improved its related Preoperative was more symptom at presentation (OR 3.348, 0.006), longer surgical time 1.005, 0.001), loss 1.000, 0.018), transfusion 2.734, higher level 4.750, 0.004) 3.449, while 7.784, 0.007). Conclusions adverse non-metastatic TT. Also, both can be clinically used for stratification patients.